Premium nutrient sources sourced from our independent production pipelines to guarantee consistent culture performance and scalable industrial yields.
In modern industrial biotechnology, the selection of raw materials directly determines the cost-effectiveness and efficiency of downstream processing. Among various organic nitrogen sources, Acid-Hydrolyzed Casein (also referred to as Casein Hydrolysate) represents a cornerstone for culture media formulation. Produced by treating casein with hydrochloric acid at elevated temperatures, this substance undergoes complete degradation of peptide bonds, resulting in a rich mixture of free amino acids, small peptides, and inorganic salts. This complete hydrolysis represents a critical process difference when compared to enzymatic digests (such as tryptone), rendering a substrate that is highly consistent and readily absorbable by microorganisms.
Global procurement teams prioritize batch-to-batch consistency above all. Industrial application requirements demand strict compliance with specifications: total nitrogen (TN) values generally exceeding 10.0%, amino nitrogen (AN) content representing over 50% of the total nitrogen, and negligible ash levels to prevent crystallization or precipitation during sterilization cycles. Achieving these targets requires sophisticated purification steps, particularly the removal of excess sodium chloride generated during the neutralization of hydrochloric acid with sodium hydroxide. Our facilities utilize state-of-the-art desalting technology to deliver low-salt formulations tailored for sensitive biotechnological operations.
In past decades, acid hydrolysis was a batch-based, labor-intensive process prone to quality drift. The transition to Industry 4.0 has transformed production. Modern operations employ automated closed-loop systems where hydrolysis duration, temperature, pressure, and acid concentrations are modulated via PLCs. This systematic approach guarantees that every batch displays identical molecular weight distribution profiles and mineral assays, minimizing variability in large-scale microbial fermentations.
Established in 2008 and rooted in the Science and Technology Innovation Area of the China (Beijing) Pilot Free Trade Zone, we have grown into a premier high-tech enterprise combining R&D, production, and global supply chains.
As a recognized national "High-tech Enterprise" and a "Zhongguancun High-tech Enterprise," Beijing Hongrun Baoshun Technology Co., Ltd. relies on independent production lines to meticulously manufacture premium microbial culture media components, including peptones, yeast extracts, and premium acid-hydrolyzed casein formulations.
In 2018, we expanded our strategy with the commissioning of Phase I and Phase II factories in the Qili Industrial Park in Langzhong, Sichuan. Spanning a production area of over 40,000 square meters and housing 20,000 square meters of modern storage space, this facility enables us to maintain continuous production and stable pricing despite changing market dynamics.
Our operation features 5 dedicated subsidiaries including Beijing Yaoyou Technology, Sichuan Baoshun Biotechnology, Sichuan Romgee Biotechnology, Sichuan Yingwen Technology, and Sichuan Runxiaobao Technology. Working in alignment under strict ISO 9001:2015 and MUI Halal quality systems, we enforce a strict standard: "no substandard products leave the factory."
Combining technological integration and raw material proximity to build a highly responsive production ecosystem.
We maintain strictly isolated production lines for animal-derived and plant-derived raw materials. This separation prevents cross-contamination, satisfying the stringent regulatory compliance requirements of global biopharmaceutical partners.
Advanced control valves, automated pH titration loops, and high-capacity spray drying towers ensure casein hydrolysis proceeds to completion. Controlled drying minimizes thermal degradation, protecting the bioavailability of key amino acids.
Our 20,000 square meter storage capacity acts as a buffer against supply chain shocks, guaranteeing that wholesale customers experience stable supply and predictable lead times regardless of international shipping disruptions.
By establishing our core manufacturing operations in Langzhong, Sichuan, we leverage local resource availability and lower operational overheads. These regional efficiencies allow us to offer competitive global pricing without sacrificing quality standards. In addition, our close proximity to logistics centers guarantees rapid transit times to major Chinese ports, ensuring swift delivery to international buyers.
Providing essential organic nitrogen across distinct microbiological, industrial, and agricultural sectors.
A primary ingredient in Mueller-Hinton Agar and caseinate-based media. Due to complete acid hydrolysis, the tryptophan is destroyed, which is useful for testing bacterial production of indole or for carrying out microbiological assays of vitamins (e.g. Nicotinic acid, Riboflavin, Pantothenic acid).
Provides critical nutrients for toxin production (such as diphtheria toxin), vaccine preparation, and antibiotic susceptibility media. High free amino nitrogen content supports fast-growing pathogen cultures under biosafety compliance.
Utilized as a high-purity raw material for downstream synthesis, fermentation process modeling, and protein expression. Consistent free amino acid compositions allow researchers to construct precise nutrient mass balances.
Used to propagate beneficial live microorganisms such as Lactobacilli. The abundance of free amino acids ensures rapid biomass accumulation during the initial growth phases, improving viability rates.
Acts as an organic source of nitrogen and bio-stimulants for eco-friendly agriculture. Amino acids chelate soil micronutrients, promoting crop absorption, reinforcing root development, and increasing yield quality.
Holding MUI Halal certification, our Acid-Hydrolyzed Casein meets the regulatory requirements for producing certified foods, beverages, and pharmaceuticals for Islamic markets.
From initial bench-scale testing to multi-ton industrial outputs, we support your production cycles through seven core strengths.
Collaborating with our expert R&D team to define your specific amino acid profile requirements, salt tolerance limits, and molecular weight expectations.
We supply free samples up to 500g per product (shipping excluded) to allow you to verify compatibility with your target strains in your own laboratories.
Customizing parameters such as spray-drying density, particle size, salt levels, and filtration clarity to integrate with your existing equipment.
Conducting strict batch testing including HPLC amino acid profiling, heavy metal detection, and solubility assays prior to packaging.
Offering volume discounts, customizable packaging formats (25kg bags, fiber drums, bulk bags), and annual supply agreements to secure your cost structure.
Coordinating customs, shipping lines, and warehousing networks to guarantee on-time delivery across Asia, Europe, and the Americas.
Answers to key technical questions from biochemical procurement teams and fermentation scientists.
Explore our full range of animal, plant, and yeast-derived nutrient sources engineered for global biotechnology applications.
Hongrun Baoshun