High-purity organic nitrogen sources designed for optimizing cell culture density and production yield.
Founded in 2008, Beijing Hongrun Baoshun Technology Co., Ltd. took root in the highly acclaimed Science and Technology Innovation Area of the China (Beijing) Pilot Free Trade Zone. Leveraging our outstanding technical strength, strict compliance matrices, and an unremitting pursuit of process innovation, we have evolved into a modern high-tech enterprise integrating research and development, large-scale production, and global supply chains.
We are honored to stand out as a distinguished recipient of dual official designations: a national "High-tech Enterprise" and a "Zhongguancun High-tech Enterprise". Our strategic goal is to support biopharmaceutical developers, probiotic cultivations, and industrial enzyme producers with highly stable, nutrient-dense organic nitrogen bases.
In 2018, the company initiated a significant scale-up by expanding its production footprint to the Qili Industrial Park in Langzhong, Sichuan. This expansion established a world-class manufacturing center that guarantees long-term supply stability for international distributors and domestic biotech groups alike.
Understanding the critical role of yeast autolysate and refined extract profiles in cellular biomass maximization.
Yeast extracts act as the engine of high-efficiency bioreactors. Produced by autolyzing selected strains of yeast, usually Saccharomyces cerevisiae, our yeast extracts provide a rich mixture of soluble peptides, free amino acids, essential B-complex vitamins, trace elements, and nucleotides. These nutrients are critical for supporting cell membrane synthesis, maintaining cell viability, and accelerating cell replication rates.
Our processing methodologies ensure that the total nitrogen (TN) content and amino nitrogen (AN) ratios remain consistent from batch to batch. By using specialized peptidase formulations during autolysis, we control the molecular weight distribution of the peptides. We optimize the peptide profile to supply the specific short-chain peptides that are easily absorbed by bacteria, fungi, and mammalian cell lines.
Furthermore, the natural presence of growth-promoting nucleotides (such as guanylate and adenylate) acts as a powerful cofactor for fastidious microbial strains that struggle to synthesize DNA precursors from scratch.
How we apply biochemical engineering and precision automation to drive future organic nitrogen innovations.
Our technical team is developing specialized enzyme cocktails to customize peptide profiles. By selecting specific endopeptidases and exopeptidases, we can target precise molecular weight distributions (e.g., matching the optimal range for recombinant E. coli vs. lactic acid bacteria). This reduces the formation of indigestible, high-molecular-weight proteins while preventing excess free ammonium accumulation, which can inhibit cell growth.
To meet the strict requirements of pharmaceutical cell cultures, we are incorporating advanced multi-stage ultrafiltration (UF) and nanofiltration (NF) loops. This technology removes unwanted macromolecular complexes, endotoxins, and mineral ions. The resulting ultra-clarified yeast extract yields a clear, residue-free solution that is ideal for downstream purification and reduces filter fouling.
Our long-term R&D roadmap focuses on breeding yeast strains that over-produce specific micronutrients, such as B-vitamins or unique organic trace minerals. This strategy helps us create specialized yeast extracts that eliminate the need to supplement fermentation media with costly synthetic vitamins.
Ensuring stable industrial capacity, precise traceability, and consistent batch-to-batch quality.
Our Sichuan facility operates fully automated animal and plant raw material processing lines. This closed-loop setup prevents cross-contamination and regulates temperature, pH, and concentration rates in real time. We rely on automated process monitoring to maintain batch stability and minimize batch-to-batch variation.
Sichuan is a major hub for raw agricultural and bio-industrial inputs, providing us with direct access to high-quality, traceable raw materials. This strong local supply chain protects us from global price fluctuations and ensures that our factory can operate continuously year-round.
With 20,000 square meters of dedicated, climate-controlled warehousing, we hold sufficient buffer stocks of raw ingredients and finished powders. This enables us to fulfill urgent bulk orders quickly and prevent supply disruptions for our global clients.
Optimizing microbial growth and product yield across diverse industrial sectors.
Our yeast extracts and peptones are widely used in dehydrated and ready-to-use culture media. They provide key nutrients that support the growth of fastidious pathogens, diagnostic strains, and environmental isolates.
These highly purified nitrogen sources serve as raw materials for manufacturing therapeutic proteins, vaccines, and monoclonal antibodies. They help maximize cell-specific productivity while keeping impurity profiles low.
We provide bulk nitrogen sources for large-scale fermentations that produce organic acids, industrial enzymes, solvents, and specialty chemicals. Our products are formulated to improve carbon-to-nitrogen conversion rates.
We supply custom nutrients designed for cultivating beneficial microorganisms, such as Lactobacillus and Bifidobacterium. These nutrients help maintain cell viability during freeze-drying processes.
Our plant- and yeast-derived nutrients are used to produce eco-friendly biopesticides, biofertilizers, and plant growth-promoting rhizobacteria (PGPR), supporting sustainable agricultural systems.
We offer specialized yeast powders and soy peptones that serve as organic nitrogen sources in aquaculture feeds, helping to support the immune health and development of aquatic species.
Our formulations support bioremediation processes by stimulating target bacterial populations to degrade complex pollutants in municipal wastewater and contaminated soils.
We supply rich organic nitrogen complexes that accelerate mycelial growth and improve crop yields in commercial mushroom cultivation systems.
Ensuring that our products meet local import regulations and strict quality standards worldwide.
Global procurement teams must balance product quality, supply reliability, and regulatory compliance. Our facilities address these needs by offering detailed document packages, including Certificate of Analysis (CoA) batches, allergen statements, BSE/TSE-free declarations, and GMO statements.
We cooperate closely with international freight forwarders to provide flexible incoterms (FOB, CIF, DDP) and custom packaging solutions, such as 25kg moisture-proof bags and bulk super sacks.
Our quality management systems are certified under ISO 9001:2015. For clients targeting specific consumer markets, we supply certified products that comply with MUI Halal requirements, ensuring clean manufacturing lines that are free from prohibited cross-contaminants.
We leverage the specialized capabilities of our five subsidiaries to coordinate R&D, production, and international sales:
Our rule: "No substandard products leave the factory." Every batch undergoes quality testing and retention analysis prior to release.
Providing tailored, end-to-end biological nitrogen solutions for our global partners.
We provide full-cycle technical support, including pre-sales consultation, process debugging, after-sales maintenance, and troubleshooting, helping to ensure the stable operation of your fermentation system.
We support personalization based on your requirements, covering raw material blend formulations, physical particle size adjustments, custom moisture content, and specialized packaging.
Our strict quality control system and standardized production processes help ensure stable product performance, high chemical purity, and consistency across production lots.
Our supply chain network and regional distribution warehouses enable efficient order processing, helping to shorten transit times for international shipments.
We offer cost-effective pricing strategies and flexible cooperation models, supporting volume discounts and long-term supply contracts to help optimize your production costs.
Our professional business team communicates in multiple languages, ensuring clear, barrier-free communication and smooth execution of international contracts.
We offer a complete after-sales support system, including clear product return and exchange policies, on-site technical training, and regular follow-up consultations.
Addressing key technical, quality, and supply questions from bio-industry procurement teams.
Specialized extracts, digests, and raw plant proteins to support diverse industrial fermentation processes.
Hongrun Baoshun